DPCstruct | MC34997

Metacluster Properties and Pfam Annotations

Number of structural domains140
Mean domain length (aa)406 ± 82 aa
Standard deviation of domain lengths82.06
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score84.33
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)21.74
Pfam Score98.50
Assigned Pfam label(s) PF00305- CL0063- CL0321

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
N1R1J6 48-501 ALHDQLFQKIPFVRKIQENSEGLLRYDTPDIIKKDKFAWLRDDEFARQALAGINPVNIQRLQVFPPVSRLDPAVYGPPGAALTEEHI…
A0A453H5G4 18-334 STITAAHIQKNLEGLTVQQALESNRLYILDHHDRFMPFLIEVNNLPGNFIYATRTLFFLRGDGRLTPLAIELSEPVIQGGLTIAKSK…
A0A6P8HBU0 49-393 None
A0A7S2UEN7 31-531 None
A0A7N0VBI8 7-380 None
A0A7N2LAR2 5-300 None
A0A2B4STF2 96-487 None
A0A7J0GDF7 3-317 None
A0A7M5UI27 107-444 None
A0A7N8XJ22 7-296 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.