DPCstruct | MC3499

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)173 ± 30 aa
Standard deviation of domain lengths30.16
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score76.80
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)23.75
Pfam Score97.62
Assigned Pfam label(s) CL0314- CL0087

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K6Q8S3 1-126 RKEKEPVVAETVEEKKEPILVCPPLRSQAYTPPEDLQSRLESYVKEVFGSSLPSNWQDISLEDSRLKFNLLAHLADDLGHVVPNSRL…
A0A4Y2JL89 36-191 KYKRPEDLEDPLYYGKGPKKEVQTALQAIADRGFGRELPSYQPPIDLNEQLHKICKKVFGSDLSSTWKEQPLNDPLMKYKVLTKCIE…
A0A1X7UA67 14-144 None
A0A653DFD6 1-139 None
A0A4C1TT07 7-168 None
A0A674G6U7 75-230 None
A0A1X2G9Q2 12-178 None
A0A835NHS9 3-133 None
A0A2C9JQ40 32-203 None
A0A6A4JJE3 200-408 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.