DPCstruct | MC34978

Metacluster Properties and Pfam Annotations

Number of structural domains13460
Mean domain length (aa)283 ± 54 aa
Standard deviation of domain lengths53.95
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score89.51
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.33
Mean intra-cluster sequence similarity (%)10.61
Pfam Score88.98
Assigned Pfam label(s) PF01265- PF06364- CL0103- CL0219- PF01341

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A257Q022 28-222 None
A0A519PJH9 3-201 None
A0A4Q3V833 137-450 None
A0A4Q3VB79 4-413 None
A0A1I7Y3M4 29-304 None
U4U1F5 33-352 None
U4U2X8 515-750 None
U4UAR7 386-709 None
A0A7V6M4Q7 312-627 None
A0A2D5YXL0 17-365 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.