DPCstruct | MC34978

Metacluster Properties and Pfam Annotations

Number of structural domains13460
Mean domain length (aa)283 ± 54 aa
Standard deviation of domain lengths53.95
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score89.51
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.33
Mean intra-cluster sequence similarity (%)10.61
Pfam Score88.98
Assigned Pfam label(s) PF01265- PF06364- CL0103- CL0219- PF01341

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A416EMV3 1-224 None
D7H7W0 2-203 None
E6X1W5 2-176 None
A0A6P0ZNW1 106-406 None
C0XLY7 47-332 None
A0A7W0XI74 33-321 None
A0A225VIR8 2-263 None
A0A0M8JQ37 77-388 None
A0A5N5MRG0 124-412 None
A0A1D2A9K6 83-447 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.