DPCstruct | MC34978

Metacluster Properties and Pfam Annotations

Number of structural domains13460
Mean domain length (aa)283 ± 54 aa
Standard deviation of domain lengths53.95
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score89.51
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.33
Mean intra-cluster sequence similarity (%)10.61
Pfam Score88.98
Assigned Pfam label(s) PF01265- PF06364- CL0103- CL0219- PF01341

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A831JZD4 5-264 GCWIWGTTVRELGIERVLKLSKDIGIKDLFLLVKSVSGIVNFSILESIGKHAIDHDLRIHTWIVCFEDKSVGSITPEDEEYRKYLLT…
A0A6D0F5A3 29-332 TLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGL…
A0A6P5GZK7 185-558 None
T2F5N3 8-405 None
R5LLT6 170-495 None
A0A1X6PEN0 67-422 None
A0A7W0QEP9 40-286 None
A0A194VAY1 8-323 None
A0A0C2JB06 2-230 None
A0A1H9MPV5 183-547 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.