DPCstruct | MC34963

Metacluster Properties and Pfam Annotations

Number of structural domains453
Mean domain length (aa)74 ± 15 aa
Standard deviation of domain lengths14.67
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score75.02
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)32.09
Pfam Score98.65
Assigned Pfam label(s) PF16664- PF01576- CL0154- CL0220- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P8GQJ8 11-77 AALERKAGSQRFSENMPHKFEIRSYKVPTFCNHCSSMLWGFMRQGLQCKACKMNVHKHCENNVAPSC
A0A498P3N9 117-173 PENGTANGHDFQMHCFEDTTSCKACQMLLRGIFYQGYRCSRCKMAAHKECLGRVPAC
A0A7S1Z0J2 59-157 None
A0A1I8IPH2 94-190 None
A0A182U053 52-122 None
A0A3Q0J584 645-713 None
A0A821QXN4 208-282 None
A0A6P5W678 73-167 None
A0A6P5VW88 376-431 None
A0A2D4FUH5 48-133 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.