DPCstruct | MC34734

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)249 ± 24 aa
Standard deviation of domain lengths24.35
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score83.38
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)19.32
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A9PPH4 9-275 IECRFMNYGWEPTLHPSSFAPFRSEPYTAEGWFSLDRGTWLLSALPPLLNQSLTMAYGGSWQELADELNSDLASIKNKRTIYEILMW…
A0A2C5Z6M7 101-363 HDCAPMRLSGSAYNFDCSELHLRYSMWCQPVNVATVVRDALPEEMLKMMLEVHGIDSNEVWRRIFKDLQKTDAQKTRLHQLRWIGDA…
A0A2C5X8H0 7-234 None
A0A2C5YGN1 6-244 None
A0A2C5Y5G1 3-276 None
A0A2C5Y0U7 782-1044 None
A0A2C5XUU7 22-258 None
A0A2C5XUI0 3-270 None
A0A2C5XM07 32-299 None
A0A2C5XIY9 133-388 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.