DPCstruct | MC34661

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)81 ± 12 aa
Standard deviation of domain lengths12.11
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score82.41
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)31.50
Pfam Score92.42
Assigned Pfam label(s) CL0044- PF06243

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A142L7N3 2-85 DNWETYEVFHQKKRGDQHMHVGIVHAPNPEMALLFGKDQYGRRGITANIWVVKTANVFCTEYEDQDMFETTPEKQYREAGGYKV
A0A2E8QWC6 2-63 REFVYDVFTRKERGDRLQHVGYVDAFDDETAKVYAWTTYSEEKWFEMCVVKRVNVLPVNRTD
A0A4Q4XII4 3-89 None
A0A3M0WXE2 5-84 None
A0A4Q4WSS5 3-87 None
A0A521XUK0 15-97 None
A0A2W5YYU0 6-72 None
K6P1U3 6-90 None
A0A800IHS5 1-80 None
A0A510HH65 2-62 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.