DPCstruct | MC34636

Metacluster Properties and Pfam Annotations

Number of structural domains108
Mean domain length (aa)194 ± 39 aa
Standard deviation of domain lengths38.84
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score74.45
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)30.90
Pfam Score71.23
Assigned Pfam label(s) CL0229- PF15815- CL0537

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5D6XXK2 461-648 LFYYGAPGEFAASDMAAPPQHSGPSKTCTYFLQGLCRYGDSCFYLHALREDVDTEDDMLEIGRELQASAELECNICYDNILQKEERF…
A0A287UL68 22-176 ICSFAAAGTCPYGEECPQTHGDLCTTCGKQCLHPYRPSEGGAHIKLCKRNNKRLEALKKSEEIECSVCLDRVLSKPTAAEKRFGLLP…
H0Z0R7 508-785 None
A0A814Q290 13-144 None
A0A3Q1GFF6 150-337 None
A0A383WCS5 10-193 None
A0A2G5UCV8 155-371 None
A0A7S2XVW4 1-218 None
G3WTM3 59-267 None
B8C7B5 7-224 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.