DPCstruct | MC3462

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)130 ± 6 aa
Standard deviation of domain lengths6.33
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score87.54
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)29.25
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0E4HAR0 101-224 KAREVEPDLEKHHFALPVLEALLNEDKGEEFTNMDTRLFDNQNVRKKFEAIGENDLYDLYYEYDTNFTHGLWGAIRESAMIFCDNPS…
U5NA05 1-124 MEPPKFINIEWIEQIAGEDIWEEFLNIELGNWSGLDLRKLSEQSGCKDQYDTHYSWTSGYVHGTWGPVREASFTTCGNPLHRMHRYP…
A0A2B7GQH2 348-472 None
A0A0C1FRH4 6-135 None
A0A7C2WLW3 1-142 None
A0A538NX10 251-374 None
A0A6P1MHV7 299-429 None
A0A2T2Q4I5 136-260 None
A0A1S1U9W5 23-153 None
A0A7Y2W5I3 387-527 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.