DPCstruct | MC34601

Metacluster Properties and Pfam Annotations

Number of structural domains5709
Mean domain length (aa)100 ± 18 aa
Standard deviation of domain lengths17.89
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.62
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)12.61
Pfam Score83.22
Assigned Pfam label(s) PF18972- PF09280- CL0003- CL0219- CL0273

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q4CSR2 509-595 None
Q4CQE9 347-438 None
E4XBX2 4-99 None
E4X6N5 299-407 None
E4X0J6 309-407 None
E4WYB6 170-244 None
A0A2I1HVR2 1-111 None
A0A075G9Q0 2-94 None
A0A5J4XXM9 3-99 None
A0A5J4XTU0 500-586 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.