DPCstruct | MC346

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)60 ± 3 aa
Standard deviation of domain lengths2.79
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score93.83
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.96
Mean intra-cluster local Distance Difference Test score0.96
Mean intra-cluster sequence similarity (%)75.10
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B8KEE5 5-65 EKVEKLIERNVIEVAPLAYMRGRTLNDAFIILDESQNTTVEQMKMFLTRIGFNSRAVITGD
A0A4Y1ZBR4 1-59 MLGAEHTLRLIERGTIEIAPLAYMRGRTLEDAYVILDEAQNTTQEQMKMFLTRLGFGSK
R0MHY0 5-62 None
A0A645IZT6 2-59 None
A0A7W1SZF0 1-64 None
A0A645I4J6 1-65 None
A0A4U9TTC4 5-65 None
A0A0N0I5E1 26-87 None
A0A6L7ZJS3 1-56 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.