DPCstruct | MC34593

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)167 ± 29 aa
Standard deviation of domain lengths29.34
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.49
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)55.73
Pfam Score98.29
Assigned Pfam label(s) PF00223- PF00124- CL0410

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3B5YXA2 1-153 MSALGRPQDMFSDTAIQLQPIFAQWVQNIHATAPGVTAPGATTSTSLACGGGELVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTV…
M1WY86 9-133 LQPVFAQWLQNLHTMAPGSSTAPNALTTVSHAFGGGAVAIGGKVAMMPIALGTADFMVHHIHAFTIHVTVLILLKGLLFARSSRLIP…
A0A7J9KA92 1-159 None
A0A2G2XC02 117-270 None
A0A5D2KKH8 298-451 None
A0A7J9KJ29 192-362 None
A0A1R3KZH4 2-206 None
A0A3Q7EC50 131-283 None
A0A3B6PKD4 324-523 None
A0A445CGY6 131-264 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.