DPCstruct | MC34494

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)521 ± 100 aa
Standard deviation of domain lengths100.40
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.28
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.41
Pfam Score96.30
Assigned Pfam label(s) CL0020- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D0IQ88 7-420 SVITDWKRLWPMVSGIHYETPQDTVREELMNVASELQAGVLQFKPKNASSLELGTLLKEKKQEKLLPFTERLQDLLDLESAQCWEIL…
A0A0F8AE74 393-948 RNPPKSAEQREKVRKASTEGIAIQGQQGSRLLPEQLLKEAFILSDLFDMGELVALELLLAGEQQQPHFPGLTRGLVAVLLYWDGRLC…
A0A177WS89 53-709 None
B8PIK2 10-750 None
D3BJS9 1-552 None
A0A6V7U2P4 22-420 None
E7EXJ6 48-626 None
A0A2G8L4V0 97-609 None
A0A835R6B9 2-445 None
A0A0N1PIH7 70-571 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.