DPCstruct | MC34452

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)218 ± 27 aa
Standard deviation of domain lengths27.20
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score68.77
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)29.75
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183WC48 1-205 MQFFSLLNKADKAKVKKLAKDRPSKKQLRAAAEMEDGTWTTIDSYGRAEVQIQAFEKGQEINFEVVVRRMEEILASRGKKGTSTSDQ…
A0A835J9F1 11-188 DDQSEKDGGWEKMMSKKDKLMDKQFAKDPSEITWDIVNKKFKEIVTARGRRGTGRFEQVEQLTFLTKVAKTPTQKLEILFSVVSAQF…
A0A376B2L8 235-435 None
E2LUV5 145-383 None
A0A6G4ZZJ5 205-449 None
A0A1S3IUF1 158-407 None
A0A7J7IG37 85-261 None
A0A7J7L534 195-424 None
A0A2R7VZW8 76-286 None
A0A396JF28 2-186 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.