DPCstruct | MC3444

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)325 ± 56 aa
Standard deviation of domain lengths56.22
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score76.84
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)35.90
Pfam Score92.31
Assigned Pfam label(s) PF05431- PF06880- CL0066

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A398AWT4 45-371 TILKTLSQFRKYQKTLSEESPEGPFSAVLVIIDEEAETDDTFCFGMCKSTKIEMLPFPQDKILSVVHTDSSGNRDTSVKKVLFIRKF…
A0A6I9Q8C4 21-387 PPEGPNSGYLVLQDEGPDVAEPTCCWGLCKDTRVRDLPFPQNRILTIEYTQPNGQSSATYTEVVIFVPVMDQPLSSNRYYVILVKGK…
A0A7G2DWJ0 104-388 None
B8BAS3 17-376 None
A0A6A2XGK4 9-307 None
A0A6P6GJJ5 276-620 None
A0A1R3HPR1 685-1051 None
A0A1J3G3M8 1-256 None
A0A0E0QIZ5 534-934 None
A0A834L885 488-790 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.