DPCstruct | MC34436

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)100 ± 16 aa
Standard deviation of domain lengths15.93
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.83
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)38.79
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A158QYK2 67-140 EEMMRTGFDFELDGLLYYHSGVVYEAGQSPLVGWLKPWMLPEILNVTVPQKFLNENLLQQSSQQFIDAFNVQHN
A0A183VWL8 2-81 QNAFSSMPSYEVDGVLFYHDDVNYEPGATPLVNWLKPYMLPEWFPNIKFHSDFMKNMPSDYTDYLNEIRQYEANSSKSLK
A0A0D8XT93 264-379 None
A0A158N7X3 227-336 None
A0A1I8FQI7 52-190 None
A0A670Z3T0 60-168 None
A0A834BNR8 1-82 None
A0A3P7G455 1-91 None
T1JE87 478-598 None
A0A183LWZ8 103-191 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.