DPCstruct | MC34394

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)116 ± 16 aa
Standard deviation of domain lengths16.43
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.25
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)38.03
Pfam Score93.81
Assigned Pfam label(s) CL0182- PF03105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3Y619 4-96 AFVEFYQKLRLLKNFCLLNVLAFSKIMKKYDKITSRKASKSYLEMVNKSYLGSSDEVAKLIERVEATFIKHFVNGNRRKGMKSLRPQ…
A0A819VNU1 3-97 AFSELYLLLVLLQNYQTLNYMGFKKILTKHDKLFHKINGIEWFKTNIDSSPFVSNQQVSNLIDEVEILVTDHLENVNRKKAMQKLRV…
A0A1R3JKN6 197-295 None
A0A4S2MR19 221-347 None
A0A445J029 87-187 None
L0P8S7 18-127 None
A0A565BRE9 171-269 None
A0A0L7L6F9 31-162 None
A0A1X7T578 33-145 None
I1C2E5 150-257 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.