DPCstruct | MC34391

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)95 ± 14 aa
Standard deviation of domain lengths13.52
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score71.35
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)48.46
Pfam Score97.14
Assigned Pfam label(s) CL0023- CL0137- PF04571

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q5ZIR2 6-101 QLAGQVLVTVKELYKGINQATLSGCIDVVVVRQQDGTYQCSPFHVRFGKLGVLRSKEKVIDIQINGDAVDLHMKLGDNGEAFFVQET…
A0A6G0I6Z1 59-154 QLAGQVFVQVKELYRGLNPATLSGCIDVIVVRQPDGSLQCSPFHVRFGKMGVLRSREKVVDMEINGEPVDLHMKLGDNGEAFFVQET…
A0A673BMJ1 1-77 None
A0A673BK23 23-116 None
A0A2G8L4T0 2-83 None
F4Q1P4 53-135 None
A0A5M3MAP2 1-113 None
A0A4S4CYR6 1-109 None
A0A0V0QB29 4-104 None
A0A6I9PQ03 63-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.