DPCstruct | MC3437

Metacluster Properties and Pfam Annotations

Number of structural domains70
Mean domain length (aa)291 ± 72 aa
Standard deviation of domain lengths71.68
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score77.13
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)25.77
Pfam Score94.70
Assigned Pfam label(s) CL0220- CL0208- CL0649

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3P6Q934 1-172 MEVDYGITQYLGDRSISVPCVMKELYSDFIVQEILEDETVLRLATASEVRSYVKEEEEKGVDEAVDVPSSLSAEQVTALDALDKNSK…
A0A5N6MJY0 5-312 LEESDVGISCYISPLPGFRGILKQRYSDFVVNEVDLDGNIVHLTSLEAPTEIAKEPETKTIDQLNGNYGTEIESFRALAGDSDANCL…
A0A183E7R5 2-246 None
A0A2V2VTU6 14-233 None
A0A7J6PVU7 42-354 None
A0A7J6PE54 47-486 None
R7UEY7 70-247 None
A0A3Q0KLJ9 18-292 None
A0A3Q7ENG9 46-339 None
A0A3P6TW53 4-230 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.