DPCstruct | MC3435

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)228 ± 35 aa
Standard deviation of domain lengths34.53
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score76.96
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)19.32
Pfam Score100.00
Assigned Pfam label(s) PF14953

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C3PF27 16-284 VCTSVQGVLEMFSALRHVHKSKLQQFSFDITVIAFALRCGYLFDAFGLRRHQTELQDFLAEVLTKLRDMLPVFESVTLLYDPASVQI…
A0A5N6M8I1 4-264 SEALRVLNSSLSRINWRLKPSSKRRFETDILALCMGLRPVIMIDYGGKMPELRDRLCAFVKFSQGESSIFENIRIMVIEDMIYLIDV…
A0A162U304 1-181 None
A0A4W3GPE6 5-207 None
A0A2C9KE39 23-236 None
A0A4S4DC63 31-222 None
A0A0F7S5W0 28-255 None
F4Q3A9 35-294 None
A0A7N0TU91 1-253 None
A0A5C3MI18 7-235 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.