DPCstruct | MC34280

Metacluster Properties and Pfam Annotations

Number of structural domains32
Mean domain length (aa)72 ± 7 aa
Standard deviation of domain lengths7.36
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score78.72
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)56.23
Pfam Score100.00
Assigned Pfam label(s) PF16135

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A835RC28 333-397 EKMPCVAARGPDGKTVTGFLYRYTKEEVNIVCVCHGRSFSPAEFLRHAGSSETSQALRRIIVVSS
A0A251SCH6 76-137 EKMPCVTTKVGKRIQGFLYRYGEDEEVRIVCVCHGSFLTPAEFVKHGGGGEVEHPLRHIVVT
A0A2K2DUD0 43-106 None
A0A6A4PL59 75-148 None
A0A3Q7EZT7 1-65 None
A0A151TCH3 154-227 None
I1H839 18-101 None
A0A7J0ERX1 189-256 None
A0A5N6PCU1 266-340 None
A0A3B6G2D4 148-224 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.