DPCstruct | MC33987

Metacluster Properties and Pfam Annotations

Number of structural domains3313
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.61
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.59
Pfam Score95.88
Assigned Pfam label(s) CL0020- CL0194- PF16178- CL0219- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2N8U8U2 22-238 None
O35948 35-240 None
S3C7F8 20-242 None
A0A235I1D9 2-216 None
A0A395STK2 460-679 None
A0A6N3U9J8 2-151 None
U6KLW3 283-495 None
H2ATI2 242-473 None
A0A220VEN6 4-189 None
A0A6D2LKQ2 9-141 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.