DPCstruct | MC33987

Metacluster Properties and Pfam Annotations

Number of structural domains3313
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.61
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.59
Pfam Score95.88
Assigned Pfam label(s) CL0020- CL0194- PF16178- CL0219- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5N3VJ53 32-245 None
A0A2K9YPI6 224-424 None
A0A5P9XPW8 5-157 None
X7YXD3 2-151 None
X7ZWE8 2-136 None
X8DDB0 2-126 None
A0A821X5Y2 39-220 None
A0A1Y4TNY8 47-239 None
A0A4D8YX54 111-298 None
A0A848UZJ9 572-738 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.