DPCstruct | MC33987

Metacluster Properties and Pfam Annotations

Number of structural domains3313
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.61
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.59
Pfam Score95.88
Assigned Pfam label(s) CL0020- CL0194- PF16178- CL0219- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7I8W2G8 103-296 None
A0A177UM14 165-395 None
K8ZCB7 123-337 None
A0A7W4INF9 46-237 None
V5EU27 20-249 None
A0A1B3WDY5 7-181 None
A0A818NFE2 21-256 None
A0A818PLF6 90-341 None
A0A6A5HR60 81-245 None
A0A433Q0S5 19-185 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.