DPCstruct | MC33987

Metacluster Properties and Pfam Annotations

Number of structural domains3313
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.61
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.59
Pfam Score95.88
Assigned Pfam label(s) CL0020- CL0194- PF16178- CL0219- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067PGM8 8-144 None
A0A2H9ZSM4 134-276 None
A0A2I0A141 151-391 None
A0A1J6J5K5 256-400 None
A0A3D3V355 226-406 None
A0A1L7WTT3 133-371 None
A0A428VD86 112-299 None
A0A6M2A0Y7 409-618 None
A0A6C0LPC5 14-209 None
A0A533I0D9 160-381 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.