DPCstruct | MC33987

Metacluster Properties and Pfam Annotations

Number of structural domains3313
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.61
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.59
Pfam Score95.88
Assigned Pfam label(s) CL0020- CL0194- PF16178- CL0219- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H9TP02 448-549 None
A0A257V3C4 4-154 None
A0A1L7VQP9 7-241 None
A0A6P8SVX0 205-418 None
A0A212KRR0 16-282 None
A0A2G2G8K5 2-183 None
A0A376VJ02 52-221 None
A0A2M7YTY8 4-188 None
M5FU40 50-233 None
A0A2H9TFZ3 75-199 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.