DPCstruct | MC33987

Metacluster Properties and Pfam Annotations

Number of structural domains3313
Mean domain length (aa)192 ± 35 aa
Standard deviation of domain lengths34.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.61
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.59
Pfam Score95.88
Assigned Pfam label(s) CL0020- CL0194- PF16178- CL0219- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1K2IWG7 3-161 KQKILVIDLETTGLDPFTDYIVSIAISVEKGKGFNIVLPFYKNKAKAKEFLQPILPLLEDETITKVFHNAKFDLKFFHQYCIEIKGE…
A0A093IHA8 1-128 MTGLDVEKDQILEMACLITDSDLNVLAEGPNLIINQPDELLESMSEWCKEHHGKSGLTKAVKESKISLQQAEYEFLSFVRQQTPPGL…
A0A0P1AWU1 52-267 None
A0A3D3P143 196-354 None
A0A0P1B1C8 888-1105 None
A0A1L9TKP6 5-171 None
A0A6I6L5I5 32-234 None
A0A6G1IN35 13-136 None
F6H7B6 6-177 None
A0A5N6E5P2 53-243 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.