DPCstruct | MC33963

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)247 ± 33 aa
Standard deviation of domain lengths32.72
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.59
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)32.84
Pfam Score100.00
Assigned Pfam label(s) PF12432

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3P7J0N8 26-233 MCRMKPMSAERQALISAMAVTLASGQATWDPYYVTAFLHDSLGDRNWVNKPNTSFISTQIIKSLGTIYPTKDMFTSCNLEIDVDFIP…
A0A183U2W2 14-206 CCIFSVLYSILKDSGEWPWTLVECFVDDSLHERRWVDRVCAGALVDNIITAFGTTPPNEELYTACELTYPERFQHKQVVRDRFAELA…
A0A6J1WXM6 2-202 None
A0A194RM30 125-381 None
A0A814E3U7 198-484 None
A0A0R4IJ75 159-421 None
F1KUS3 24-228 None
K7H0M0 58-380 None
A0A0K0D0Z1 71-298 None
A0A2P8XQA9 67-334 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.