DPCstruct | MC33951

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)155 ± 28 aa
Standard deviation of domain lengths28.11
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.01
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)38.05
Pfam Score91.58
Assigned Pfam label(s) CL0020- PF12807

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453FK68 53-163 IVRAFKHIVQSVIAATSDMRQLALTIAAVLNLLLGVPESEFSGSSPAVHPLVWRWLVAFLKKRYQYELTGQHYDDVRKYAILRGLCH…
A0A3P7ILY2 3-192 SLSVTELIARCAKHVLRQYLNSLPQEQLGCAISHLLNAVFGNLSFDHSYGMNGDRNTKRSSKKSKKAFASGEWVAVNTKEFWSALCQ…
A0A2I0GBK3 1-153 None
A0A453FK87 1-117 None
A0A453FKA4 54-214 None
A0A453FKA5 11-167 None
A0A453PVL2 1-153 None
A0A1X7TLM3 86-232 None
A0A0K0E7J3 1458-1653 None
E7FE02 1181-1371 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.