DPCstruct | MC3394

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)125 ± 12 aa
Standard deviation of domain lengths12.47
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score84.10
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)20.06
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A078RDM3 2-107 LKEKGFNEPCMIAMNIEDGRQYGTNRTNSELPIKVCSHPTQSVAQKWLRKTKNLHIEISYMYENYWTYDILTIPRHDLIGLSDRPII…
A0A7K3KS46 6-136 IDSFVTYEQAQNLKELGYNEKGYFFFSRTFCDDGTPVIVHKGFVIPPTNEEMDDIGMENHISAPTHSQAARWLRGKKMSVEVEYNIG…
A0A7J0B1N8 1-125 None
A0A1V6I3B3 1-132 None
A0A7C6K915 2-116 None
A0A843HDQ1 1-106 None
A0A1M3LAI9 1-141 None
J6IJH4 43-161 None
A0A4Q0J667 1-127 None
A0A250F5I8 3-152 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.