DPCstruct | MC33929

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)70 ± 4 aa
Standard deviation of domain lengths3.82
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score85.66
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)50.59
Pfam Score100.00
Assigned Pfam label(s) PF00858

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H2JMM7 1-69 MSRLPAPYGDCVPDGKTSDYIYSSYEYSVEGCYRSCFQQLVLKECRCGDPRFPVPENARHCDAADPVAS
A0A6P4VFL6 33-107 LERKGEPYSQCTMNGSDVPVRNLYSDYNTTYSIQACIRSCFQDHMIRNCSCGHYLYPLPRGQRYCNNREFPDWGE
F1L2M7 6-78 None
A0A1Y3ELX9 291-354 None
A0A158PML8 254-323 None
A0A0B1SJW2 203-272 None
A0A3P7KVZ9 25-94 None
A0A7E4V225 495-568 None
A0A0C2DBL7 1-75 None
A0A0C2BPD7 59-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.