DPCstruct | MC33911

Metacluster Properties and Pfam Annotations

Number of structural domains718
Mean domain length (aa)160 ± 26 aa
Standard deviation of domain lengths25.94
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.47
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)14.43
Pfam Score96.24
Assigned Pfam label(s) CL0126- CL0345- PF03945- CL0056- PF13963

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E4MWN8 33-184 None
A0A428PRB1 358-527 None
A0A0E0DTN5 548-757 None
A0A835VXE6 372-530 None
A0A7S3WTZ6 208-341 None
A0A0C4ECX7 506-673 None
A0A0U1LXY5 1-157 None
A0A833QNZ9 6-140 None
A0A833QWC4 126-309 None
A0A2G2W142 28-183 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.