DPCstruct | MC33911

Metacluster Properties and Pfam Annotations

Number of structural domains718
Mean domain length (aa)160 ± 26 aa
Standard deviation of domain lengths25.94
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.47
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)14.43
Pfam Score96.24
Assigned Pfam label(s) CL0126- CL0345- PF03945- CL0056- PF13963

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6M7Z6Z3 585-733 None
A0A812IL02 238-375 None
A0A5N5SWY6 37-174 None
A0A5N5T5K6 34-204 None
A0A816YHD8 4-144 None
A0A1D6LHA2 84-217 None
A0A6A2YHD4 104-241 None
A0A5J5B4E2 251-437 None
A0A1C7MK05 77-242 None
A0A3Q3D0X1 2-117 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.