DPCstruct | MC33911

Metacluster Properties and Pfam Annotations

Number of structural domains718
Mean domain length (aa)160 ± 26 aa
Standard deviation of domain lengths25.94
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.47
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)14.43
Pfam Score96.24
Assigned Pfam label(s) CL0126- CL0345- PF03945- CL0056- PF13963

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y7QLK7 611-749 None
A0A7S0CY18 397-523 None
D3BIA7 267-432 None
A0A3Q9Y0W0 8-194 None
A0A498LEL4 496-635 None
A0A498M278 208-382 None
A0A287QDI6 267-498 None
G4ZAY9 13-141 None
A0A1V6TKF8 28-185 None
E4UXJ7 14-170 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.