DPCstruct | MC33845

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)150 ± 17 aa
Standard deviation of domain lengths17.15
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score82.44
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)26.91
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1E1WQS8 246-387 KPLKALNATLSEHNLDLFYQAVDVSLSECGMILKKVDKKKDKLLIQNHREKLISELEICDDPALVLHLAVLAIYTIITQNMLHASGR…
A0A7S0WTS5 16-165 AALAQASGALGAESLAEVASVIEAAASDMGLRVRRLDKKSEKAAVASERSRLLGSLSGESDPAAALALVVPLVFMKATGHALALPGK…
A0A8B6DHE2 1-126 None
A0A7J7JAF1 15-175 None
S9WKJ5 130-270 None
A0A7R9DHT2 20-156 None
T1FQH7 711-872 None
A0A6V7W431 2-146 None
A0A0D2MD11 884-1059 None
A0A1S3Y2E1 2-137 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.