DPCstruct | MC33840

Metacluster Properties and Pfam Annotations

Number of structural domains238
Mean domain length (aa)98 ± 15 aa
Standard deviation of domain lengths14.95
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score75.33
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.20
Pfam Score96.24
Assigned Pfam label(s) PF00082- CL0570- PF00958- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A287RR97 16-98 DYEHWLIVMDKPGGEGASKHQMIDCYIQTLAKVLGSEEEAKKKIYNVSCERYFGFGCEIDEETSNKLEGIPGVLFMLPDSYVD
A0A6A3ARF0 2-82 VRTYEKICAQGLGISVDEAKKRIYACSTSTYEGFQVLMSEEESEKFNDVPGVVFVLPDSYIDPVNKEYGGDKYENGVITQR
M7Y800 4-112 None
A0A396ICS0 1-96 None
A0A5B6VX62 12-118 None
A0A445D965 56-161 None
A0A6D2HVE9 68-192 None
A0A803Q4W1 340-450 None
A0A2G3D4V0 109-192 None
A0A7N2KM15 560-640 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.