DPCstruct | MC33835

Metacluster Properties and Pfam Annotations

Number of structural domains231
Mean domain length (aa)216 ± 42 aa
Standard deviation of domain lengths42.02
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.89
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)18.65
Pfam Score98.91
Assigned Pfam label(s) PF13976- CL0458- PF04998- CL0030

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A287RGZ1 2-223 LILHGTKTSAVLNSVLADFFHLKRDHAVKFTKKNDSIRPFESGGETSLEFFSLKSDCSLLVYGSHSKKRPNNLVLGRTYDHHIYDLV…
E2ACN1 4-186 LYDLKKPNAQMMQKKNDILPFENIVPIEKFAFKYEASLFMMASHNKKRPNNLVMGRMYDHMLLDMIEFGIENYKGLKDFKVEKVSLG…
A0A1N6LY28 7-267 None
A0A0F7SN49 117-333 None
A0A0P0VXB6 10-199 None
A0A811MLG6 145-376 None
A0A812QC86 590-827 None
A0A1V9YWR4 73-284 None
A0A2V0PL44 24-200 None
H2C6L3 5-136 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.