DPCstruct | MC33778

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)155 ± 24 aa
Standard deviation of domain lengths24.31
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.57
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)26.41
Pfam Score84.72
Assigned Pfam label(s) PF06996- PF05947- CL0763

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3M2YF07 9-165 AAALTTLSQHIREYSVYQAIPLILGVLREVHPDADDEQLHAFLELRANPSLGFPCSDIERLDFFHEHTDLYVRLYLNVMSLVGSGSP…
A0A2X3ENQ5 11-150 MNFYRFCQLLEKNHPKAPLIGSGWLVGDEPIRFRPHPGMGFPAGEIRGMDDPEPPRPPAVRVTFMGLYGVESPLPTHYSDDIAQRRE…
A0A1H4BHJ2 154-348 None
A0A812R4E3 279-453 None
A0A399I9Y7 1-163 None
A0A5M0YLB4 7-133 None
A0A484YXW9 112-259 None
A0A4V1XRP7 770-943 None
A0A377LXW1 12-146 None
G1Y226 597-787 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.