DPCstruct | MC33774

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)79 ± 6 aa
Standard deviation of domain lengths5.81
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score87.62
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)57.20
Pfam Score100.00
Assigned Pfam label(s) CL0104

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A379AFL9 1-76 MGIQGTHTARFGEIEQRGVALTPQGRALYDRLLSEAGSGQDNQQHQQHLAAIFRDFPDDETTLRQQELAWFPLSPE
A0A455UZT6 102-177 GHHTARFGEIEQRGVALTQKGRALYDQLLAQSRQLPAAQDNATHQAHLAEVFQAFPDDLDTLRREGLAFFHYYAAP
A0A2G1C481 1-69 None
A0A4Q3QAT3 179-255 None
A0A748M7W2 213-298 None
A0A376THA2 98-183 None
A0A376KUK1 187-266 None
A0A7G2IU32 99-169 None
A0A455UGJ0 15-97 None
U3TVC6 1-75 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.