DPCstruct | MC33757

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)157 ± 17 aa
Standard deviation of domain lengths17.25
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score85.35
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)20.52
Pfam Score75.00
Assigned Pfam label(s) PF08977- PF08955

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y4UQA1 59-216 TENTDDNTVKTENVDNTEDHLQMVIADNTITESTKMVYQYYYKNEGVMEESEEVPPYFLLGFDFNDMLEYYPDWQIVSFSSKEVVMR…
A0A4R6MWF0 90-219 REVHMITTFICGTETTEMGQLKAGSIAELLEQHPDWHARLNTKGELWVDRQVEDLSPLCKKQAYMGMNREGQLTLFEGPPKKDKVIR…
A0A645G8Y0 5-148 None
A0A3B9SPI4 7-160 None
A0A0M0L7I3 1-143 None
A0A7X8FBQ9 36-213 None
A0A229P057 43-200 None
A0A3E0QQU2 176-340 None
A0A2K8N7X1 1-180 None
W7Z7Y6 1-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.