DPCstruct | MC33704

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)138 ± 22 aa
Standard deviation of domain lengths21.76
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score73.48
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)25.31
Pfam Score74.82
Assigned Pfam label(s) PF07965- PF08725- CL0257

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0J7KNB6 23-133 EGVETVIVDVDNDEVPCFGTDEDDCKYNFVYYYNETNCLQVRAQNERECPPQVYMLGIVLGVIAAVVLVGLALLLLWKLLTTIHDRR…
A0A4Z2CI26 161-312 CQTKLNCIECLGFNIGPFKGNCSKACSTVVPDTVSQLNKEVKHCELKDSESCWIKFSLEQLDGVDTYKAVIQSERVCPEPPSVTAII…
A0A5B7CMK8 37-179 None
A0A067REL8 20-146 None
A0A4Y2U9D3 1-110 None
A0A3P9K9L5 381-525 None
A0A0C2JDH3 28-197 None
A0A0C2M9X4 15-191 None
A0A6I9YEL6 186-329 None
A0A482WEE8 289-463 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.