DPCstruct | MC33622

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)139 ± 13 aa
Standard deviation of domain lengths13.09
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score91.24
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)39.16
Pfam Score100.00
Assigned Pfam label(s) CL0059

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H9TNJ8 303-435 SDSITLLLPHFERNLRWFTRTQHGNLHPALEAQSSAGLYRWRGRSKHYTLTSGLEDYPRGTTPNEYELHVDLAAWMAFAARTLRRLR…
A0A183AIR0 236-381 RQWSLTALPRLHTWYQWFNRTQAGSVPFSYYWKGRDPHEIHQLNPLTLSSGLDDYPRASHPSNTERHLDLRCWMALFARTVARLASL…
A0A820ZZJ6 226-375 None
A0A418AG34 76-225 None
A0A453GCF5 157-287 None
A0A5E4R1Q3 221-332 None
A0A3P6SH83 1-148 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.