DPCstruct | MC33616

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)175 ± 32 aa
Standard deviation of domain lengths31.74
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score74.74
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)18.39
Pfam Score33.33
Assigned Pfam label(s) CL0229- CL0144

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6F9AIM8 17-167 RLSPLFFEYPAEIKSEKGRINFKHRILRENPETLFADCSQNGTVTNLLFYTDHTTAWHTAVTSHFSYTTKKGICKGRQIHIFEDSDK…
A0A6J8DPU1 7-180 TSARTKSKPQPYTLAKYENFNINKTRALACNRTKDINIEEKHQNYILELSAAAYEVLKGEIDIYFEHYTYKLMPKHQYDNQGLCIRT…
A0A7D9HI67 417-647 None
K1RXB5 15-216 None
A0A444U8I4 1-152 None
A0A444U4B2 21-179 None
A0A8B6DWF1 9-185 None
C3Y6U7 9-178 None
A0A6J8BB48 5-222 None
A0A8B6DPS3 1-180 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.