DPCstruct | MC33597

Metacluster Properties and Pfam Annotations

Number of structural domains137
Mean domain length (aa)138 ± 23 aa
Standard deviation of domain lengths23.38
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.42
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)18.93
Pfam Score66.67
Assigned Pfam label(s) CL0123- PF18367

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H1SA79 4-133 ENLVDEWMTVPDLADALGTTASRARGVVSDRRVLGVRRGERATFQIPAKFVVSRREEQIASGKGAPVDAADDRRVVLSSLAGTITVL…
A0A512BV21 10-136 DPLAPSLARNVEHRQTLLVSAGGAVSAEAAGQVLGITRQAVDKRRRAGTVLAVREGSDWRYPACQFDNGEVLAGIADVVRGFGSAGP…
A0A4S0VKH8 44-164 None
A0A1X0UHQ8 18-166 None
I5CWY6 97-233 None
A0A6G3UZC1 14-104 None
A0A7C8B926 48-176 None
A0A1X7IUC3 105-263 None
A0A7W0A957 73-209 None
A0A522KIB3 153-311 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.