DPCstruct | MC33583

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)146 ± 15 aa
Standard deviation of domain lengths15.30
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score83.21
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)37.17
Pfam Score100.00
Assigned Pfam label(s) CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M3Y187 65-198 ETTDEDEDGGSEKKYRRCEKSGCTVACPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYMAWKKIWTSNGK…
H2YJH2 1-136 KHEEKPEISEKEKQIFLNKHSCKKSGCHKVGLTCCIQATNACMEASGKSSRWYHVSLEEHYCNGKNSGCDDFHEWKKAWMNNSKADA…
A0A1S3ISL1 224-354 None
A0A3S1B194 182-334 None
A0A4W3HST3 1-172 None
A0A5K4F5A3 16-149 None
A0A812DJD0 46-178 None
A0A5J4NFP0 7-179 None
A0A0N4Y0V5 31-169 None
A0A3B4D2A1 62-199 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.