DPCstruct | MC33576

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)190 ± 33 aa
Standard deviation of domain lengths32.54
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score68.75
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)23.51
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H2YCQ8 7-212 PPLSYKKWILRGSGSIAGHVSPGSVVLSPFDQMRTASVLGGFNASVSSNSPTMAQYVTVGTSPFVGFSYALDGSSQPLLSHVALAVA…
F2DT59 170-357 LQIMLQKSFQEVKSRMWKDKFEQEDDEDTSSFEKTPLQIWNVSKFGSCVDAAIVGLMPPPLLELQSSQRHYCAITVGEDAVVSAYRL…
A0A453KLB5 30-189 None
A0A4Y2FZ59 4-154 None
A0A1I8GXY8 1-195 None
U9SV61 169-382 None
A0A1A9WZT5 1-150 None
A0A367JJM3 5-188 None
A0A177WN01 15-253 None
A0A1R1XAM9 74-289 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.