DPCstruct | MC33548

Metacluster Properties and Pfam Annotations

Number of structural domains87
Mean domain length (aa)127 ± 30 aa
Standard deviation of domain lengths30.03
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score86.67
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)28.39
Pfam Score79.44
Assigned Pfam label(s) PF04561- CL0410- PF04563- PF04565- PF04566

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A199YUI2 5-121 GTFINNGSERLIVSQLVRSPGSYFHLKADKNGLESFGHTTIPNRGAWFELDTDAKGIGYVRIDRTRKLTFTTMLRALGFGSDEEILE…
W1DQD2 110-211 MGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIIL…
A0A4W5PG09 79-259 None
A0A1V5JVL6 70-160 None
Q8HTL6 219-359 None
A0A396I4D4 5-100 None
A0A345HH11 109-250 None
A0A820V5C5 32-207 None
G6C2T1 126-218 None
A0A7R9KBR6 5-124 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.