DPCstruct | MC33536

Metacluster Properties and Pfam Annotations

Number of structural domains93
Mean domain length (aa)217 ± 36 aa
Standard deviation of domain lengths35.97
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.58
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.71
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6M6JFB0 18-198 RRLWNRAPTVGHVAELMAWFCLGELQSWPGHDGPTDPETREANLGPVLAHACRSGFITTGSQPGIDRDPEDGFEQRAAVDGLATAEV…
A0A139HPS7 20-257 ADGDDWQRLWNDAESWQGFLDANRAFLRGEMSQSPYYHAQISEETKPLVESLLKLHDYGFLTYCSQPSRDDKDAYFIERDCCAKCGN…
A0A4D4KS78 13-193 None
B5VIK4 184-408 None
A0A146H906 368-594 None
A0A0C2YK55 245-464 None
A0A5B1QRE1 232-452 None
A0A6A5UCN9 2-252 None
A0A7D9LEC5 112-287 None
A0A4U0VEC5 364-587 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.