DPCstruct | MC33508

Metacluster Properties and Pfam Annotations

Number of structural domains5
Mean domain length (aa)240 ± 6 aa
Standard deviation of domain lengths6.03
Length coefficient of variation0.03
Mean AlphaFold2 pLDDT confidence score88.73
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)50.04
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S8RAU8 1-245 MYLQKSLLWQSEPYPFDVIRWMCHIDENGREHNWTAVDGQYKRTFLQQNSANIKVELKSPMTNEYYQGRDAAEKGINRKDLYDKAVF…
A0A7X7CL34 194-429 LERKLFWTSKPHMFNVVRLMYHMDENGNLGAPEQVDCQYQRNFTQQNTGKINWSIPASMGANYKRSREAAKRQDTRNSELDRAVFAS…
A0A1E3BVB6 1-230 None
A0A7X3CMV5 460-703 None
A0A2K9E0J2 198-442 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.